Find a product for my lab

Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder
Devyser Placeholder

Devyser Placeholder

Cystic fibrosis

A broad selection of genetic test kits for detection of variants in the CFTR gene. Allele-specific CFTR mutation detection and complete CFTR gene sequencing using NGS.

Contact me

CFTR mutation testing can be used in diagnosis of cystic fibrosis, male infertility caused by CBAVD, and acute recurrent or chronic pancreatitis. It can also be used to guide targeted therapies, and as an aid in newborn screening. More than 2,000 mutations and variants in the CFTR (cystic fibrosis transmembrane conductance regulator) gene have been described. The vast majority of these mutations have a population frequency below 0.1 % with high heterogeneity of mutation distribution between different ethnic groups. Devyser’s range of diagnostic CFTR kits enables allele specific detection as well as targeted, complete, CFTR gene sequencing using NGS for detection of all mutations, known and unknown, in a single test.

The Devyser CFTR kits are easy to implement and highly cost-effective, making them a good match for laboratories of any size. With ready-to-use reagents and a user-friendly workflow, they suit both manual and automated workflows.

Related articles

Whitepaper: Next Generation Sequencing: Changing the game in CFTR analysis

Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders – updated European recommendations

Scientific publications

F508del CFTR gene mutation in patients with allergic bronchopulmonary aspergillosis. M. N. Gamaletsou et al., J Asthma. 2018 Aug;55(8):837-843.

Analysis of the CFTR gene inVenezuelan cystic fibrosis patients, identification of six novel cysticfibrosis-causing genetic variants. Sánchez K et al. Appl Clin Genet. 2016; 9:33–38.

No items found.