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Devyser AZF v2

Devyser’s unique single-tube approach simplifies the workflow, reduces hands-on time and minimises the risk of sample mix-up and contamination during both basic and extended AZF analysis.

  • Detect all markers needed for basic AZF deletion screening
  • One tube per sample means no need for sample splitting
  • Conforms to EAA and EMQN best practice guidelines

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Devyser AZF v2

Devyser’s unique single-tube approach simplifies the workflow, reduces hands-on time and minimises the risk of sample mix-up and contamination during both basic and extended AZF analysis.

  • Detect all markers needed for basic AZF deletion screening
  • One tube per sample means no need for sample splitting
  • Conforms to EAA and EMQN best practice guidelines

Testing according to EAA and EMQN best practice guidelines

All STS markers and control sequences, recommended by the European Academy of Andrology (EAA) and the European Quality Monitoring Network Group (EMQN) for basic molecular diagnosis of Y-chromosomal microdeletions in the AZFa, AZFb and AZFc regions are included in the kit. If a suspected deletion is detected an extended AZF marker analysis should be done using the Devyser AZF Extension kit.

The use of fluorescently labelled primers for all markers allows automated visualization and identification of the STS markers using a Genetic Analyzer. Thus, eliminating multiple PCR reactions, use of toxic chemicals associated with the use of EtBr stained Agarose gels, and the guesswork associated with fragment identification

AZF testing kits

Diagnostic testing using Devyser AZF v2 relies on PCR amplification of sequence-tagged sites (STS) in the AZFa, AZFb and AZFc regions on the Y-chromosome. Successful amplification of an STS marker indicates presence, whereas absence of PCR amplification is indicative of deletion.

Devyser AZF v2 – for basic deletion testing

Devyser AZF v2 allows detailed analysis of Y-chromosome microdeletions in the AZFa, AZFb and AZFc regions. Conforms to the EAA and EMQN best practice guidelines for basic molecular diagnosis of Y-chromosomal microdeletions. Combine with Devyser AZF Extension for a complete basic and extended workflow

Devyser AZF Extension – for extended deletion analysis

Conduct extended molecular diagnosis of Y-chromosomal microdeletions in the AZF region using Devyser AZF Extension. Conforms to the EAA and EMQN best practice guidelines for extended molecular diagnosis of Y-chromosomal microdeletios

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Product Details

CE-IVD

Devyser AZF v2 CE-IVD
Chromosome Y microdeletion detection: AZFa: sY86, sY84 AZFb: sY127, sY134 AZFc: sY255, sY254 Controls: ZFY/ZFX, sY14 (SRY)
8-A019.2
Pack size: 
25

RUO

Devyser AZF v2 RUO
Chromosome Y microdeletion detection: AZFa: sY86, sY84 AZFb: sY127, sY134 AZFc: sY255, sY254 Controls: ZFY/ZFX, sY14 (SRY)
8-A019.2-RUO
Pack size: 
25