The availability of newly detected variants in open databases combined with the efforts to improve the capacity to interpret and communicate detected variants, will facilitate the improved counseling of tested patients.

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Devyser HBOC NGS

The Devyser HBOC gene panel has been developed with an integrative approach towards the varying literature and expert recommendations for follow-up after negative BRCA testing. It can also be employed as a first-line protocol simultaneously with BRCA1 and BRCA2, extending the screening by an additional 12 genes. Its purpose is to pinpoint mutations in genes with a recognised connection to the development of breast and ovarian cancers.

  • Targeted sequencing of 12 genes relevant for hereditary breast and ovarian cancers (HBOC)
  • From sample to sequencing within one day
  • End-to-end CE-IVD solution

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Devyser HBOC NGS

The Devyser HBOC gene panel has been developed with an integrative approach towards the varying literature and expert recommendations for follow-up after negative BRCA testing. It can also be employed as a first-line protocol simultaneously with BRCA1 and BRCA2, extending the screening by an additional 12 genes. Its purpose is to pinpoint mutations in genes with a recognised connection to the development of breast and ovarian cancers.

  • Targeted sequencing of 12 genes relevant for hereditary breast and ovarian cancers (HBOC)
  • From sample to sequencing within one day
  • End-to-end CE-IVD solution

Quick and easy implementation

With ready-to-use reagents, less than 45 minutes hands-on time and customised data interpretation software, it is a good match for laboratories of any size. The targeted sequencing approach combined with uniform coverage of target regions maximises the output of relevant sequencing data in every run.

Identify variants to guide testing of at-risk relatives

Genetic testing of these genes may help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing of at-risk relatives. This test is specifically designed for heritable germline mutations.

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Product Details

CE-IVD

Devyser HBOC for NGS
Sequence variants in 12 genes known to significantly increase the risk of developing breast and ovarian cancer in germline samples. They are ATM, BARD1, BRIP1, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53
8-A111-24
Pack size: 
24
8-A111-48
Pack size: 
48

RUO

Devyser HBOC for NGS
Sequence variants in 12 genes known to significantly increase the risk of developing breast and ovarian cancer in germline samples. They are ATM, BARD1, BRIP1, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53
8-A111-24-RUO
Pack size: 
24
8-A111-48-RUO
Pack size: 
48