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Devyser Thrombophilia

The Devyser Thrombophilia assay offers a very simple procedure for testing six relevant mutations implicated in the risk of developing thrombophilia and venous thromboembolism.

  • One single mix for testing of six relevant risk factors for thrombophilia
  • Single-tube PCR
  • Fast analysis with minimum hands-on time

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Devyser Thrombophilia

The Devyser Thrombophilia assay offers a very simple procedure for testing six relevant mutations implicated in the risk of developing thrombophilia and venous thromboembolism.

  • One single mix for testing of six relevant risk factors for thrombophilia
  • Single-tube PCR
  • Fast analysis with minimum hands-on time

The Devyser Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of developing thrombophilia and venous thromboembolism (VTE).

It is a multiplex PCR reagent kit for simultaneous detection of six genetic risk factors associated with thrombophilia:

  • Factor V Leiden, G1691A/R506Q.
    One of the most important genetic risk factors for inherited thrombophilia, found in 20-50% of patients with VTE.
  • Factor V R2, H1299R.
    Compound heterozygosity for FV R2 and FV Leiden is associated with an increased risk for venous thrombosis compared to that seen in FV Leiden heterozygotes alone.
  • Prothrombin/Factor II, G20210A.
    Carriers have elevated risk for thrombosis; significantly increased risk in combination with FV Leiden.
  • 5,10-Methylenetetrahydrofolate Reductase (MTHFR), C677T.
    Homozygosity predisposes to thrombosis in the presence of additional risk factors.
  • MTHFR, A1298C.
    Compound heterozygosity for MTHFR C677T and MTHFR A1298C is considered a risk factor for cardiovascular disease.
  • Plasminogen Activator Inhibitor 1 (PAI-1/ SERPINE1) 4G/5G.
    The 4G allele is considered to be a mild risk factor for VTE and Myocardial Infarction.

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Product Details

CE-IVD

Devyser Thrombophilia
Factor V Leiden, Factor V R2, Prothrombin/Factor II, MTHFR C677T, MTHFR A1298C and corresponding wildtype alleles, PAI-1/SERPINE1 4G and 5G
8-A035
Pack size: 
48

RUO

Devyser Thrombophilia
Factor V Leiden, Factor V R2, Prothrombin/Factor II, MTHFR C677T, MTHFR A1298C and corresponding wildtype alleles, PAI-1/SERPINE1 4G and 5G
8-A035-RUO
Pack size: 
48