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Insights
Transplantation

The importance of implementing early diagnostics after hematopoietic stem cell transplantation (HSCT)

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for patients with malignant or non-malignant hematological diseases.
Case study
Thalassemias

How CING of Cyprus transformed their thalassemia testing with NGS

How CING of Cyprus transformed their Thalassemia testing with NGS
Insights
Transplantation

Chimerism monitoring: is there a new gold standard on the horizon?

NGS technology is enabling improved chimerism monitoring, with novel strategies that combine the benefits of STR-PCR and qPCR into a single assay.
Insights
Fetal RHD screening NIPT

Literature review - NIPT for fetal RHD status using an exon 4-based assay

We summarize the findings of three seminal publications that support clinical implementation of the single-exon detection strategy for fetal RHD screening.
Insights
Fetal RHD screening NIPT

RHD screening just got easier: how single exon NIPT testing helps

In RhD-negative mothers, anti-D prophylaxis can be withheld if the fetus is also RhD-negative. Fetal RHD status testing with NIPT is efficient and low risk.
Insights
Fetal RHD screening NIPT

Prevent RhD disease without overtreatment: how NIPT optimizes administration

Non-invasive prenatal testing (NIPT) can help us determine fetal RhD status without a drop of fetal blood. Learn more.
Technology
Thalassemias

Guide to NGS test implementation - simpler, faster, better

This NGS guide addresses frequently asked questions and highlights key factors to consider when adding a new NGS test to your offering.
Insights
Thalassemias

Genetic testing for alpha and beta thalassemia testing just got a lot easier. One patient – one reaction

Next-generation sequencing (NGS) testing can be used for simultaneous analysis of HBA and HBB gene clusters.
Insights
Thalassemias

Alpha- and beta-thalassemia – can one test meet all needs?

Difference between alpha- & beta-thalassemia testing, as well as new technologies to determine thalassemia variants that can reduce turnaround time.
Technology
Thalassemias

The NGS workflow

These are the traditional four steps in an NGS workflow - nucleic acid extraction, library preparation, sequencing, data analysis.
Technology
Thalassemias

NGS testing in clinical practice - what to expect

Staffing requirements, breadth of assay technologies, assessing the impact on workflows
Insights
Fetal RHD screening NIPT

Fetal RHD screening using a single-exon approach; safe and accurate

The use of multiple exons for fetal RHD detection is regarded as superior to the single-exon approach to minimize the risk of false negative results.
Insights
Accessories

Devysers IVDR learnings

157 rigorous pages, 113 articles, and 15 well-thought annexes. That is the executive summary of Devyser’s IVDR journey. Worth it? – Every day of the week!
Case study
Transplantation

A new NGS-based method for chimerism monitoring

New, highly sensitive and precise methods for mixed chimerism analytics
Insights
Thalassemias

Challenges in Thalassemia diagnosis

Thalassemia is typically caused by sequence variants in the HBA1, HBA2 or HBB genes.

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