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Insights
Transplantation

Chimerism monitoring: is there a new gold standard on the horizon?

NGS technology is enabling improved chimerism monitoring, with novel strategies that combine the benefits of STR-PCR and qPCR into a single assay.
Insights
Fetal RHD screening NIPT

Literature review - NIPT for fetal RHD status using an exon 4-based assay

We summarize the findings of three seminal publications that support clinical implementation of the single-exon detection strategy for fetal RHD screening.
Insights
Fetal RHD screening NIPT

RHD screening just got easier: how single exon NIPT testing helps

In RhD-negative mothers, anti-D prophylaxis can be withheld if the fetus is also RhD-negative. Fetal RHD status testing with NIPT is efficient and low risk.
Insights
Fetal RHD screening NIPT

Prevent RhD disease without overtreatment: how NIPT optimizes administration

Non-invasive prenatal testing (NIPT) can help us determine fetal RhD status without a drop of fetal blood. Learn more.
Technology
Thalassemias

Guide to NGS test implementation - simpler, faster, better

This NGS guide addresses frequently asked questions and highlights key factors to consider when adding a new NGS test to your offering.
Insights
Thalassemias

Genetic testing for alpha and beta thalassemia testing just got a lot easier. One patient – one reaction

Next-generation sequencing (NGS) testing can be used for simultaneous analysis of HBA and HBB gene clusters.
Insights
Thalassemias

Alpha- and beta-thalassemia – can one test meet all needs?

Difference between alpha- & beta-thalassemia testing, as well as new technologies to determine thalassemia variants that can reduce turnaround time.
Technology
Thalassemias

The NGS workflow

These are the traditional four steps in an NGS workflow - nucleic acid extraction, library preparation, sequencing, data analysis.
Technology
Thalassemias

NGS testing in clinical practice - what to expect

Staffing requirements, breadth of assay technologies, assessing the impact on workflows
Case study
Transplantation

A new NGS-based method for chimerism monitoring

New, highly sensitive and precise methods for mixed chimerism analytics
Insights
Thalassemias

Challenges in Thalassemia diagnosis

Thalassemia is typically caused by sequence variants in the HBA1, HBA2 or HBB genes.
Product update
Transplantation

Devyser launches first NGS-based test for mixed chimerism

Devyser Chimerism is an NGS library kit which enables both screening and monitoring using a single reaction mix.
Whitepaper
Oncology

Easily identify BRCA1 and BRCA2 genetic mutations

Read more about simple identification of both BRCA1 and BRCA2 genes in the whitepaper
Insights
Rapid aneuploidy analysis

Principles of QF-PCR

QF PCR analysis includes amplification, detection and analysis of chromosome-specific DNA sequences known as genetic markers or small tandem repeats (STRs).
Insights
Rapid aneuploidy analysis

STR markers

A short tandem repeat (STR or microsatellite) is a pattern of two or more nucleotides that are repeated directly adjacent to each other.

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